This course examines current issues in health policy and global health governance shaping our world in the 21st century. There is increasing recognition of the development threats from health problems – from emerging infectious diseases to the recognition that global climate change and some commercial practices are contributing to new or re- emerging health threats. We will review some of the specific issues in health policy that constitute the major lines of work of global health development agencies: infectious disease threats, refugee and humanitarian health, and chronic diseases related to diet and behavior such as tobacco use. We will review the global actors and agreements and controversies, the impact of other sectoral policies such as global trade. Students will understand the global burden of diseases, how it varies by social, economic, and demographic conditions, the social and economic determinants and impacts of ill health, and policy and implementation challenges. At the completion of this course, students should have an understanding of global health policy and other sectoral policies that affect health, the global architecture of health policy making, governance, funding and technical assistance, the key global health issues facing the world, and how health policies are intricately related to global processes and global transfer of health risk, through global trade, global agreements (e.g. climate change) and the prioritization of funding for certain health programs over others.